Coming soon
Biochemistry II
Course objectives:
This course will enable the students to –
- Explain the structural elements of proteins, its configuration, classification and details of protein denaturation and its utility in daily life.
- Understand the detailed catabolic and anabolic pathways of protein and nucleic acid metabolism.
- Enlighten about Bioenergetics and the law of Thermodynamics involved in biological processes.
- Knowledge about various kinds of minerals, their availability, transportation, metabolism and deficiency disorders.
Course Outcomes (COs):
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Course |
Learning outcomes (at course level) |
Learning and teaching strategies |
Assessment Strategies |
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Paper Code |
Paper Title |
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ZOL 211 |
Biochemistry-II |
The students will be able to CO 24: Explain the structural elements of proteins, its configuration, classification and details of protein denaturation and its utility in daily life. CO 25: Understand the detailed catabolic and anabolicpathwaysof protein and nucleic acid metabolism. CO 26: Elaborate Bioenergetics and the law of Thermodynamics involved in biological processes. CO 27: Perceive in-depth knowledge about various kinds of minerals, their availability, transportation, metabolism and deficiency disorders. |
The approach in teaching: Interactive Lectures, Discussion, Tutorials, Reading assignments, Demonstration, Team teaching
Learning activities for the students: Self-learning assignments, Effective questions, Simulation, Seminar presentation, Giving tasks, Chart preparation |
Assessment Strategies Class test, Semester end examinations, Quiz, Solving problems in tutorials, Assignments, Presentation.
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Proteins-
Classification & structural properties
Amino acids & peptides- Properties & structure
Configuration:Primary,Secondary,Tertiary,Quaternary
Ramachandran Plot, Protein Sequencing
Protein denaturation
Protein Metabolism and Diseases
- Catabolism of amino acids – Transamination, Transdeamination, Oxidative Deamination and non oxidative deamination, Decarboxylation, Synthesis of Urea(Ornithine cycle)
- Inborn errors of Protein metabolism (Alkaptonuria, Phenylketonuria, Maple Syrup, Tyrosinemia, Albinism Urea Disorders)
Nucleic Acid And Nucleotides
Structural Properties and Functions
Nucleic Acid: Catabolism, Biosynthesis
Bioenergetics:
- First and Second law of Thermodynamics
- Standard free energy change
- High energy phosphate compounds (ATP, GTP, Creatinine phosphate)
Mineral Metabolism: (Source, Daily intake, Transportation, Absorption Functions, Deficiency and Diseases)
- Iodine,
- Zinc
- Iron
- Calcium,
- (Transport and Metabolism )
- Biochemistry; Stryer, L; Freeman Publications.
- Textbook of Medical Biochemistry; Ramakrishnan, S. Prasanan, K.G and Rajan, R.: Orient Longman, Madras
Suggested Readings:
- Outlines of Biochemistry; Conn, E.E. and Stumpf P.K. ; John Wiley, New York.
- Principles of Biochemistry; Smith; McGraw hill, New York.
- Biochemistry, D.Voet and J.G.Voet, John Wiley & Sons, (2nd Edition), 1995.
- Principles of Biochemistry, Lehninger , Nelson and Cox, (3rd Edition), 1999.
- Principles and Techniques in Biochemistry and Molecular Biology, Edited by Keith Wilson and John Walker, Cambridge University Press, (6th Edition), 2007.
- Biochemistry and Molecular Biology by W.H. Elliot and Daphne C. Elliot, Oxford University Press, (3rd Edition), 2005.
- Biochemistry, J. David Rawn, Panima Publishing Corporation, 1st Indian Reprint, 2004.
- Physical Biochemistry, D Friefelder, W.H. Freeman & Company, 17th Reprint, 1999.
- Understanding Chemistry, CNR Rao, University Press, Hyderabad 1999.
- A Biologist's Guide to Principles and Techniques of Practical Biochemistry, K.Wilson& KH Goulding, ELBS Edition 1986.
- Essentials of Molecular Biology, David Friefelder, Jones and Barllett Publications,7th Reprint, 2001.
