BIOCHEMISTRY I

Paper Code: 
ZOL 114
Credits: 
3
Contact Hours: 
45.00
Max. Marks: 
100.00
10.00
Unit I: 
UNIT I

·         Water as a solvent, Ionization of water, weak acid and weak bases

·         pH, pK and buffer

·         Types of chemical bonding

Electrovalent ,Covalent and non- covalent bond, H-Bond, Van der Waals interaction, Hydrophobic interactions

10.00
Unit II: 
UNIT II

Carbohydrates

  • Classification, Structure & properties (monosaccharides & polysaccharides)
  • Glycoproteins and Glycolipids
  • Metabolism- Oxidation of glucose through Glycolysis, Krebs cycle, Gluconeogenesis, Pentose phosphate pathway & Oxidative phosphorylation(ETC).
  • Glycogenesis and Glycogenolysis.

 

10.00
Unit III: 
UNIT III

Lipids

  • Classification, Structue  & properties (Fatty acids, triglycerides, phospholipids, sphingolipids, Gangliosides)
  • Biosynthesis of Triglycerides
  • Beta-oxidative pathway of fatty acids

 

9.00
Unit IV: 
UNIT IV

Enzymes:

·         Classification, Properties

·         Mechanism of Enzyme action, activation energy

·         Kinetics (Michaelis-Menten Equation)

·         Factors affecting enzyme action

Enzyme Inhibition

6.00
Unit V: 
UNIT V

·         Inborn errors of carbohydrate metabolism( Galactosemia, Lactose Intolrence, Glycogen storage diseases)

  • Inborn errors of lipid metabolism (Phenylketoneuria, Maple syrup urine disease, Niamen pick disease, Tay sach’s disease,

Vitamins (Occurrence, Function, Requirement, Deficiency diseases

Essential Readings: 
  • Tortora, G.J. and Derrickson, B.H. (2009). Principles of Anatomy and Physiology, XII Edition, John Wiley & Sons, Inc.
  •  Widmaier, E.P., Raff, H. and Strang, K.T. (2008)
  • Vander’s Human Physiology, XI Edition., McGraw Hill
  • Principles of Biochemistry; Smith et.al; Mc Graw Hill, New York.
  • Textbook of Medical Biochemistry; Ramakrishnan, S. Prasanan, K.G and Rajan, R; Orient Longman, Madras
  • Conn, E.E. and Stuff, P.K. Outlines of Biochemistry, John Wiley New York.
  • Donald Voet and Judith G. Voet Biochemistry, John Wiley and Sons., New York.
  • Lubert Stryer, Biochemistry International Student edition W.H. Freeman and Company, New York.
  • Metzler, D. Biochemistry, Academic Press.
  • Leninger, A.D. Principles of Biochemistry, CBS Publishers and Distributors, Shahdra, Delhi.
  • Jain,J.L. Fundamentals of Biochemistry ,S.Chand publishers New Delhi.
  • Murray, R.K., Harper’s Biochemisttry; Appleton and Lange , Norwalk,Connecticut.
  • Text Book of Medical Physiology; Chatterjee, M.N and Shinde, R.; Jaypee brothers.
  • Berg, J. M., Tymoczko, J. L. and Stryer, L. (2006). Biochemistry. VI Edition. W.H Freeman and Co.
  • Nelson, D. L., Cox, M. M. and Lehninger, A.L. (2009). Principles of Biochemistry. IV Edition. W.H. Freeman and Co.
  • Murray, R.K., Granner, D.K., Mayes, P.A. and Rodwell, V.W. (2009). Harper’s Illustrated Biochemistry. XXVIII Edition. Lange Medical Books/Mc Graw3Hill.
  • H.S. Srivastava, Element of Biochemistry, Rastogi Publications Meerut.
  • Text Book of Medical Physiology; Chatterjee, M.N and Shinde, R.; Jaypee brothers.
  • U. Satyanaryana . Biochemistry IV Edition, Elsevier (2013)

 

 

Academic Year: 
2016-2017
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