Biocatalysis

• Classification and nomenclature of enzymes
• Mechanism of enzyme action
• Enzyme kinetics
• Inhibition of enzyme
• Isoenzymes and co-enzymes

Energy consideration

• Biological oxidation and reduction
• Fundamental reactions of biological oxidation

Redox potential and electron transfer system enzymes

Carbohydrates

• Definition , general properties, classification and configuration of carbohydrates

Metabolism

• Catabolism of glycogen and glucose, details of glycolysis , Krebs cycle and Cori’s cycle
• Phosphogluconate pathways(pentose phosphate pathway)

Synthesis of glycogen; glycogenesis and gluconeogenesis

Inborn errors of metabolism

Lipids

• Definition, general properties and classification
• Structure and importance of -:
  1. Simple lipids- fats and wax
  2. Compound lipids- phospholipids, glycolipids, aminolipids and sulpholipids
  3. Steroids- cholesterol, bile acids, steroid hormones
  4. Lipoproteins

 Lipid Metabolism- Beta oxidation and Lipogenesis.

Inborn errors of metabolism

General properties and classification of proteins

• Amino acid structure and classification
• Structure of protein-Primary, Secondary, Tertiary and Quartenary
• Ramachandran plots
• Globular and fibrous protein- motif in globular proteins
• Protein sequencing

Protein metabolism

• Amino acid degradation:Deamination reaction- Oxidative and non oxidative deamination reaction, transamination and transdeamination, Decarboxylation, Ornithine cycle of urea formation , Fate of carbon skeleton of amino acids(Metabolism of individual amino acid excluded)

Inborn errors of metabolism