Biocatalysis

•     Classification and nomenclature of enzymes

•     Mechanism of enzyme action

•     Enzyme kinetics

•     Inhibition of enzym

•     Isoenzymes and coenzymes

Energy consideration

•     Biological oxidation and reduction

•     Fundamental reactions of biological oxidation

•     Redox potential and Electron transfer system enzymes

Carbohydrates

    Definition , general properties, classification and configuration of carbohydrates

Metabolism

    Catabolism of glucose with Stoichiometry, Glycolysis , Krebs cycle and Cori’s cycle

    Phosphogluconate pathways(Pentose Phosphate Pathway)

Glycogenesis, Glycogenolysis and Gluconeogenesis

Inborn errors of metabolism: Galactosemia, Lactose Intolerance, Glycogen storage diseases.

Lipids

    Definition, general properties and classification

    Structure and importance of -:

        Simple lipids- fats and wax

        Compound lipids- phospholipids, glycolipids, amino lipids and sulpho lipids

        Steroids- cholesterol, bile acids, steroid hormones

        Lipoproteins

        Lipid Metabolism- Beta oxidation and Lipogenesis.

        Inborn errors of metabolism: Niemann pick disease, TaySach’sdisease, Gaucher’s disease, Krabbe’s disease

General properties and classification of proteins

•         Amino acid structure and classification

•         Structure of protein-Primary, Secondary, Tertiary and Quaternary

•         Ramachandran plots

•         Globular and fibrous protein- motif in globular proteins

•          Protein sequencing

Protein metabolism

    Amino acid degradation:Deamination reaction- Oxidative and non oxidative deamination reaction, Transamination and Transdeamination, Decarboxylation, Ornithine cycle of urea formation , Fate of carbon skeleton of amino acids(Metabolism of individual amino acid excluded)

Inborn errors of metabolism:  Alkaptonuria, Phenylketonuria, Maple Syrup, Tyrosinemia, Albinism ,Urea Disorders.