Basics of Neuroscience & Toxicology

Paper Code: 
DZOL703 T
Credits: 
4
Contact Hours: 
60.00
Max. Marks: 
100.00
Objective: 

Course

Learning outcomes

(at course level)

Learning and teaching strategies

Assessment Strategies

Paper Code

Paper Title

DZOL703 T 

BASICS OF NEUROSCIENCE 

The students will be able to-

CO1: Appraise different areas of neuroscience and

CO2: Describe and understand structure and function of the nervous system

CO3: Explore  Cellular and Molecular aspects of  Neurobiology

CO4: Value Neuropharmacology of Behaviour

CO5: Understand  types of Toxicity and its mechanisms 

Approach in teaching:

Interactive Lectures, Discussion, Tutorials, Reading assignments, Demonstration, Team teaching

 

Learning activities for the students:

Self-learning assignments, Effective questions, Simulation, Seminar presentation, Giving tasks, Field practical

Class test

Semester end examinations,

Quiz

Assignments

Presentation

Individual and group pro

 

10.00
Unit I: 
UNIT I
Introduction to Neuroscience and Nervous system
● Neuroscience; Neuroanatomy, Neurophysiology, and Systems Neurobiology Introduction to the structure and function of the nervous system: Cellular components: Neurons; Neuroglia; Neuron doctrine; 
● Functional architecture of a neuron, 
● Origin and propagation of nerve impulse,
14.00
Unit II: 
Unit II
Cellular, Molecular Neurobiology and Neurotransmitters 14 Hrs 
● Molecular and cellular approaches used to study the CNS 
● Synapse:  Types of synapses; synaptic function; 
● Principles of chemical synaptic transmission;
● Different types of neurotransmitters– catecholamines, amino acidergic and peptidergic neurotransmitters;
● Transmitter gated channels; G-protein coupled receptors and effectors, neurotransmitter receptors; Ionotropic and metabotropic receptors.
 
14.00
Unit III: 
Unit III
Neurobiology and Neuropharmacology of Behaviour 14 Hrs 
● Information processing in the vertebrate central nervous system, 
● Relationship of functional properties of neural systems with perception and behavior
● Sensory systems, molecular basis of behavior including learning and memory.  
● Molecular pathogenesis of pain and neurodegenerative diseases such as Parkinson’s, Alzheimer’s, psychological disorders, addiction, etc. 
 
12.00
Unit IV: 
Unit IV
Introduction of  Toxicology               
● History and Scope of Toxicology
● Classification of Toxic Agents : Pesticides and Metals  
● Interaction of Chemicals : Additive,Synergistics, Potentiation, Antagonism
● Dose Response relationship: Acute,Subacute,Subchronic,Chronic
10.00
Unit V: 
Unit V
Mechanisms of Toxicity                                                                      
● Delivery and Exposure
● Absorption
● Distribution
● Excretion
● Brief about specific responses of toxicity : Mutagenicity and Teratogenecity
Essential Readings: 
ESSENTIAL READINGS: 
• Casarett and Daull’s Toxicology: The basic science of poisons. By : Curtis D. Klaassen 6th Edn., McGraw-Hill (Medical Publishing Div. NewYork
• Environmental Biotechnology – by. Indu Shekhar Thakur, I.K. International Pub.(2006)
• Toxicology, Principles and Applications: Raymond I.M.. CRC Publication.
• Microbial Ecology: Fundamentals and Applications by Atlas Bartha (An imprint of Addison Wesley Longman Inc)
• Environmental Microbiology: Maier R.M., Academic Press. 2000 Press, Cambridge. 1993.
• Environmental Science- A global concern; Cunningham W.P. and Saigo B.W Win. C. Brown Publishers, London, 1995.
• Advances in Industrial Waste Water Treatment; P.K. Goel; Technoscience Publications. Jaipur, 1999.
• Neuroscience: Exploring the brain by Mark F. Baer; Barry W. Connors. 2015  
• From Molecules to Networks: An Introduction to Cellular and Molecular Neuroscience by John H. Byrne. Ruth Heidelberg and M. Neal Waxham  
• Neuroscience-Eds. Dale Purves et. al. (3rd Edn)-Sinauer Associates, Inc.-2004  
• Principles of Neural Science-4th Edn-Eds. Kandel, Schwartz and Jessell- McGrawHill Companies-2000  
• Nerve Cells and Animal Behaviour-2nd Edn-Peter J Simmons and David YoungCUP-2003  
 
Academic Year: 
2023-2024
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