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It is a University which is committed to excellence and overall development of the student and one where talent is nurtured and honed in the best possible manner. Come, be a part of our never-ending journey of accomplishments and accolades.

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Admissions

It is a University which is committed to excellence and overall development of the student and one where talent is nurtured and honed in the best possible manner. Come, be a part of our never-ending journey of accomplishments and accolades.

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Placements

Excellent education not only imparts knowledge, but also paves the way for a promising and successful career. The Placement Cell at The IIS University has numerous success stories to narrate in this regard...

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Life@IIS Univ

Life @ IISU is nothing less than a kaleidoscope of myriad hues; complete with vibrant events and memorable occasions to cherish for a lifetime.

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Academics

Taking the age-old tradition of enlightenment through education forward, The IIS University - in its continuous pursuit of excellence - firmly believes that an institution’s academic profile determines its worth and value. Therefore, on offer are a wide variety of both conventional and contemporary programmes of study.

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Research

To stimulate curiosity and cater to the global needs of a dynamic education, The IIS University - since inception - has been promoting and encouraging research-based experiential learning among all its students.

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About Us

The IIS University, with its perfect amalgamation of innovation, inspiration and synergy, aims to be a model institution for students across disciplines and programmes.

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IIS Univ
  • Admissions

    It is a University which is committed to excellence and overall development of the student...

  • Placements

    Excellent education not only imparts knowledge, but also paves the way for...

  • Life@IIS Univ

    Life @ IISU is nothing less than a kaleidoscope of myriad hues; complete with...

  • Academics

    Taking the age-old tradition of enlightenment through education forward,...

  • Research

    To stimulate curiosity and cater to the global needs of a dynamic education,...

  • About Us

    The IIS University, with its perfect amalgamation of innovation, inspiration...

IIS (Deemed to be University)

Gurukul Marg, SFS, Mansarovar, Jaipur 302020, (Raj.) India

Phone:- +91-141-2400160-61, 2397906-07,

Fax: 2395494,2781158, Toll Free No.: 1800 180 7750

Advanced Toxicology | Zoology

Advanced Toxicology

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Paper Code: 
LSC 144 I
Credits: 
4
Contact Hours: 
60.00
Max. Marks: 
100.00
12.00
Unit I: 
UNIT I
Principles of Toxicology 
• Introduction of toxicology 
• Different areas of toxicology 
• Toxicology and Society 
• General characteristics of the Toxic Response 
• Classification of Toxic Agents
• Spectrum of Undesired Effects : Allergic and Idiosyncratic reactions, Immediate versus delayed toxicity. Reversible v/s Irreversible Toxic Effects. Local v/s systemic Toxicity. Interaction of chemicals
• Characteristics of Exposure 
• Dose-Response Relationship 
• Variation in Toxic Responses 
• Descriptive Toxicity Tests 
• Toxicogenomics 
12.00
Unit II: 
UNIT II
Toxic Effects of Metals (I)
• Metal as Toxicants 
• Movement of Metals in the Environment 
• Mechanism of Metal Toxicity 
• Metal-binding Proteins and Metal Transporters 
• Pharmacology of Metals 
• Exposure, Toxicokinetics, Mechanism of Toxicity and Toxicity of Arsenic and Beryllium 
 
12.00
Unit III: 
UNIT III
Toxic Effects of Metals (II)
• Exposure, Toxicokinetics, Mechanism of Toxicity and Toxicity of Cd., Pd, Cu & Fe
 
12.00
Unit IV: 
UNIT IV
Chelation in Metal Intoxication 
• Chelating agents, Chemistry, Pharmacology and Toxicology
• Therapy; Combination therapy, Limitations 
• Oxidative Stress in Metal Toxicity, Role of antioxidants 
• Therapeutic Recommendations for Heavy Metal Poisoning
Nanotoxicology :
 
• Nanoparticles : Naturally Occurring and Anthropogenic nano-sized material
• Physico-chemical characteristics as Determinants of Biological activity.   
• Human Exposure to Nano-sized Materials 
• Concept of Noanotoxicology; Ecotoxicological studies, ROS Mechanisms of Nano-sized Pesticide Toxicity, Immunogenicity of nanopesticides. 
 
12.00
Unit V: 
UNIT V
Immunotoxicity  
• The Immune System; Antigen Recognition 
• Innate Immunity, Acquired Immunity 
• Inflammation, Immune – Mediated Disease
• Developmental Immunology 
• Methods to Assess Immunocompetence 
• Immune Modulation by Metals 
• Xenobiotic – Induced hypersensitivity and autoimmunity with reference to metals only.
 
Essential Readings: 
Books Recommended:
• Casarett, & Doull’s. (2008). Toxicology: The Basic Science Of Poisons (7th Ed.). New York: Mcgraw-Hill.
• Helferich, W., & Winter, C. K. (2001). Food Toxicology. Crc Press.
• Hodgson, E. (2010). A Textbook Of Modern Toxicology. A John Wiley & Sons, Inc.
• Pandey, K., Shukla, J. P., & Trivedi, S. P. (2011). Fundamentals Of Toxicology. New Central Book Agency.
• Sharma, P. (2005). Environmental Biology And Toxicology. Meerut: Rastogi Publication.
• Shaw, I., & Chadwick, J. ( 1998). Prinicples Of Environmental Toxicology. Taylor & Francis Ltd.
• Wright, D. A., & Welbourn, P. (2002). Environmental Toxicology. New York: Cambridge University Press.
 
Academic Year: 
2021-2022
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