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Environmental Toxicology I [1]

Paper Code: 
ZOL-323(C)
Credits: 
4
Contact Hours: 
60.00
Max. Marks: 
100.00
Objective: 

OBJECTIVES- The course objective is to provide students with a detailed  understanding of:

  1. Different branches of toxicology
  2. Toxicant present in the nature
  3. Their effect on environment and living organisms

 

10.00
Unit I: 
UNIT I

History and Scope of Toxicology

Principles of Toxicology

  • Different Areas of Toxicology
  • Classification of Toxic Agent
  • Spectrum of Undesired Effects

Interaction of Chemicals

  • Additive
  • Synergistics
  • Potentiation
  • Antagonism

Dose Response

  • Individual or Graded
  • Response Relationships
  • Quantal Dose
  • Dose Response Curves

Variation in Toxic Responses

  • Selective Toxicity
  • Species Differences
  • Individual Differences

Animal Toxicity Tests

  • Acute
  • Subacute
  • Subchronic
  • Chronic
  • Development and Reproductive Toxicology
  • Mutagenicity

Skin and Eye Irritation

15.00
Unit II: 
UNIT II

Mechanisms of Toxicity

  • Delivery
  • Absorption
  • Distribution
  • Excretion
  • Cellular Dysfunctions and resultant toxicities
  • Repair or Dysrepair

Biotransformation of Xenobiotics

  • Phase I Enzymes (Hydrolysis, Reduction, Oxidation
  • Phase II Enzyme Reactions (Glucuronidation, Sulfation, Methylation, Acelylation, Amino-acid conjugation Glutathione Conjugation, Phosphorylation)

Risk Assessment

  • Hazard Identifications (Assessing Toxicity of Chemicals)
  • Risk Characterization
  • Risk Perception & comparative Analysis of Risk

Environmental Impact Assessment

10.00
Unit III: 
UNIT III

Specific Responses of Toxicity

  • Carcionogenesis
  • Mutagenecity (Genetic Toxicology)
  • Teratogenecity (Development Toxicity)

 

15.00
Unit IV: 
UNIT IV

Target Organ Toxicity

  • Liver
  • Kidney
  • Nervous System
  • Blood
10.00
Unit V: 
UNIT V

Physicochemical nature & Effect of Toxic Agents

  • Pesticides: (General account )Organochlorine Compound, Antocholinesterase agents and pyrethroids esters
  • Metals (Arsenic,Lead, Mercury)
  • Industrial Solvents(General account)

Radiation & Radioactive materials

Academic Year: 
2019-2020 [2]

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IIS (Deemed to be University), Jaipur

Gurukul Marg, SFS, Mansarovar, Jaipur 302020, (Raj.) India Phone:- +91-141-2400160-61, 2397906-07, Fax: 2395494, 2781158

Source URL: https://zoology.iisuniv.ac.in/courses/subjects/environmental-toxicology-i-0

Links:
[1] https://zoology.iisuniv.ac.in/courses/subjects/environmental-toxicology-i-0
[2] https://zoology.iisuniv.ac.in/academic-year/2019-2020