Objectives
The course objectives to provide students with a basic understanding of:
Learning outcomes- By the end of the course, students will be able to:
Chromosomes: Morphology, Chromonema, Chromomeres, Telomeres, Primary & secondary constrictions, Chromatids
Chromosome type- Polytene&Lampbrush
Chromosomal Organization: Euchromatin, Heterochromatin , Nucleosome concept
Nucleosides, Nucleotides
DNA
DNA structure(A, B, Z type)
RNA structure & types( mRNA, rRNA, tRNA)
Replication of prokaryotes (Semi-conservative mechanism: Experiments of Messelson& Stahl)
Prokaryotic Polymerases, Topoisomerases, Single stranded binding protein, Replication forks(Unidirectional & Bidirectional), Leading & lagging strand, RNA primers & Okazaki fragments
Brief Idea of Eukaryotic Replication( Ori sites and Enzymes involved)
Prokaryotic Transcription
Brief idea about transcription factors in eukaryotic transcription
Post Transcriptional modification in Eukaryotes
Splicing
Genetic Code
Prokaryotic translation
Translational Machinery
Translational Initiation, Elongation and termination
Essential Readings:
Suggested Reading
Links:
[1] https://zoology.iisuniv.ac.in/courses/subjects/zoology-8
[2] https://zoology.iisuniv.ac.in/academic-year/2019-2020