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IMMUNOLOGY (Theory) [1]

Paper Code: 
25DZOL501(A)
Credits: 
4
Contact Hours: 
4.00
Max. Marks: 
100.00
Objective: 

Course objectives:

This course will enable the students to –

1.  Appraise the detailed knowledge of our immune system to defend against invading pathogens in a logical fashion.

2.  Differentiate and evaluate between innate and acquired immunity; Humoral and cell mediated immunity and the consequences of its failure like autoimmunity, hypersensitivity and immunodeficiencies.

3.  Develop an understanding about the role of effector cells and molecules of the immune system as complements and antibodies.

Course Outcomes: 

Course

Learning outcomes (at course level)

Learning and teaching strategies

Assessment Strategies

Course Code

Course Title

25DZOL

501(A)

Immuno

logy

(Theory)

CO49: Distinguish primary and secondary

lymphoid organs and various cells of the

Immune      system     and                  differentiate

between immunogens and antigens.

CO50: Distinguish the major cellular and

tissue components  which comprise the

innate  and  adaptive  immune  system.

compare and contrast between systemic

and organ specific autoimmune disease

and judge the role of vaccines in artificial

and natural immunity.

CO51: Examine &

interpret     various    forms    of  antibody-

antigen  interactions  and  correlate  the

structure of different classes of antibodies

with their effector functions.

CO52: Evaluate the role of MHC in self

restriction     and      could                    differentiate

between    endogenous    and  exogenous

antigen  presentation  and develop  the

understanding about the centralized role

of cytokines in immunity.

CO53:      Summarize      the      role                of

complements    in  innate  and  adaptive

immunity and could assess the various

kinds of hypersensitive reactions and their

consequences.

CO54:Contribute   effectively  in course-

specific interaction

The approach

in teaching:

Interactive

Lectures,

Discussion,

Tutorials,

Reading

assignments,

Demonstration

, Team

teaching

Learning

activities for

the students:

Self-learning

assignments,

Effective

questions,

Simulation,

Seminar

presentation,

Giving tasks,

Chart

preparation

Assessment

Strategies

Class             test,

Semester end

examinations,

Quiz, Solving

problems                 in

tutorials,

Assignments,

Presentation.

 

12.00
Unit I: 
Overview of Immune System & Antigens

Historical perspective of Immunology, Cells and organs of the Immune system Antigenicity and immunogenicity, Immunogens, Adjuvants and haptens, Factors influencing immunogenicity B and T-Cell epitopes

12.00
Unit II: 
Innate and Adaptive Immunity

Innate immunity-Anatomical barriers, Inflammation, Cell and molecules involved in innate immunity Adaptive immunity-Cell mediated and humoral immunity

Active and Passive immunity: Artificial and natural Immunity, Vaccines and its types

12.00
Unit III: 
Immunoglobulins

Structure and functions of different classes of immunoglobulins, Antibody mediated effector functions

Antigen antibody interactions: precipitation, agglutination, Immunoassays (ELISA )

12.00
Unit IV: 
Major Histocompatibility Complex & Cytokines

Structure and functions of MHC molecules.

Endogenous and exogenous pathways of antigen processing and presentation Properties and functions of cytokines

12.00
Unit V: 
Complement System & Hypersensitivity

Components and pathways of complement activation.

Gell and Coombs’ classification and brief description of various types of hypersensitivities.

Immune dysfunctions: Brief account of autoimmunity and AIDS.

Essential Readings: 

ESSENTIAL READINGS:

●       Roitt’s essential Immunology, P. Delves, et al., 11th ed., Blackwell Publishing, 2006 ∙

●     Kindt, T. J., Goldsby, R.A., Osborne, B. A. and Kuby, J (2006). Immunology, VI Edition. W.H. Freeman and Company.

References: 

SUGGESTED READINGS:

●     David, M., Jonathan, B., David, R. B. and Ivan R. (2006). Immunology,VII Edition, Mosby, Elsevier Publication.

●     Abbas, K. Abul and Lechtman H. Andrew (2017) Cellular and Molecular Immunology. V Edition. Elsevier; 9th edition

e-CONTENT:

●     Immunology- ePG pathshala- Inflibnet centre-

●     https://epgp.inflibnet.ac.in/Home/ViewSubject?ca [2] tid=2rAs1Puvga4LW93zMe83aA ==  ∙ Immunology-NPTEL- https://nptel.ac.in/courses/102103038 [3]

e-JOURNAL:

●     Immunology- Wiley online Library- ISSN 1365-2567

●     Scandinavian Journal of Immunology-Online ISSN: 1365-3083

 

Academic Year: 
2025-2026 [4]

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Source URL: https://zoology.iisuniv.ac.in/courses/subjects/immunology-theory

Links:
[1] https://zoology.iisuniv.ac.in/courses/subjects/immunology-theory
[2] https://epgp.inflibnet.ac.in/Home/ViewSubject?ca
[3] https://nptel.ac.in/courses/102103038
[4] https://zoology.iisuniv.ac.in/academic-year/2025-2026